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. 2016 Jan 19;36(3):407–420. doi: 10.1128/MCB.00785-15

FIG 7.

FIG 7

MED16 regulates NRF2 target gene expression in human hepatoma Hep3B cells. (A) Immunoblot analysis of MED16 expression in Hep3B cells treated with control or MED16 siRNAs. (B) Relative expression levels of electrophile-responsive genes (left) and hypoxia-responsive genes (right) in Hep3B cells treated with control or MED16 siRNAs. *, P < 0.01; **, P < 0.001. (C) Relative expression of NRF2 in Hep3B cells treated with control or MED16 siRNAs. Two different MED16 siRNAs were used (siRNAs 1 and 2).