FIG 1.
(A) Alignment of amino acid sequences of loop 2 and neighboring regions in FliKC from various species. YscP is an FliK homolog in the Yersinia enterocolitica type three secretion system (TTSS). The numbers marked correspond to the positions for the residues in FliK from S. Typhimurium. Secondary structures and loops are indicated above the amino acid sequence. Highly conserved amino acids in loop 2 are shown in boxes. Accession numbers of FliK homologs are as follows: S. Typhimurium, AAD15264; Escherichia coli, AAC75010; Yersinia pestis, AJK18643; Vibrio cholerae, CSA22037; Vibrio parahaemolyticus, AAD15917; Xanthomonas campestris, CEM58400; Bacillus subtilis, AGG60999; and Yersinia enterocolitica YscP, AAF70341. (B) Three-dimensional structure of FliK. The location of LRL is indicated by a circle. (Adapted from reference 15.)