FIG 1.

Activation of the nlmA promoter by various synthetic CSPs. (A) Primary amino acid sequence of naturally occurring matured CSP molecules of various lengths. The arrow marks the SepM processing site. (B) Induction of the PnlmA-gusA reporter fusion. An assay of the β-glucuronidase activity of the ΔcomC/pIBN35 reporter strain in the presence of various concentrations of CSPs was conducted. The assays were done at mid-exponential phase, as described in the text. The experiments were performed at least three times, and the means with standard deviations are plotted.