Table 1.

Demographic and clinical features of SSc patients in the discovery and replication cohorts

	Discovery (n = 1486)	Replication (n = 1085)
Female	1307 (88.0 %)	934 (86.1 %)
Mean age ± years	54.5 ± 12.9 y	56.1 ± 12.8 y
Diffuse SSc	505 (34.0 %)	403 (37.1 %)
Disease duration	10.1 ± 8.7 y	10.9 ± 9.6 y
ACA	425 (28.6 %)	340 (31.3 %)
ATA	238 (16.0 %)	180 (16.6 %)
SSc-ILD
Yes	185 (65.6 %)	313 (61.9 %)
No	97 (34.4 %)	193 (38.1 %)

ACA anti-centromere antibody, ATA anti-topoisomerase 1 antibody, SSc systemic sclerosis, ILD interstitial lung disease