FIG 4.

Mice were infected with rMACV at 35 days after immunization with rMACV/Cd#1-GPC, rCd#1, or PBS. (A) Survival curves for the infected mice (n = 6). **, P < 0.01 for rMACV/Cd#1-GPC- versus rCd#1-immunized mice and rMACV/Cd#1-GPC- versus PBS-immunized mice by log rank analysis. (B) Average body weight change (with SEM, n = 6) after rMACV challenge. (C) Virus titers in tissues of infected mice at the terminal stage (13 to 39 dpi) and 42 dpi. A plaque assay was performed for serum samples as well as for homogenized tissues from the brain, spleen, and liver. Cd, rCd#1; M/C, rMACV/Cd#1-GPC. Dashed lines, the minimum detection limit.