FIG 5.

Humoral response induced by FMDV A12-P1 deopt in mice. (A) Neutralizing antibodies in sera of mice inoculated with FMDV A12-P1 deopt or A12-WT before (dpi) and after (dpc) challenge. Titers are expressed as the inverse dilution of serum yielding a 50% reduction of virus titer (log₁₀ TCID₅₀/ml). Each data point represents the mean (± SD) for each group. (B and C) Systemic IgG (B) and IgM (C) antibodies in sera of mice inoculated with indicated doses of FMDV A12-P1 deopt or A12-WT before (dpi) and after (dpc) challenge. Each data point represents the mean (± SD) for each group.