FIG 5.
Ability of rgRSV grown in the presence of a cathepsin L inhibitor to infect HAE cells. The infectivity for HAE cells of partially purified rgRSV virions that were produced in HeLa or Vero cells in the presence of a cathepsin L inhibitor or DMSO (Fig. 3, the left two lanes of each panel) was tested. HAE cells were inoculated with equal numbers of HeLa cell-infectious units of these 4 viruses, as were HeLa cells, on the same day and from the same dilution series for comparison. The ratio of the number of infected HAE cells to the number of infected HeLa cells is plotted. Data from three experiments were combined. *, P < 0.01 (unpaired, 2-tailed t test); **, P < 10−4 (unpaired, 2-tailed t test).