TABLE 1.

Binding kinetics of soluble CDV H ectodomain to soluble SLAM ectodomains

Ligand	ka (1/s)	kd (1/s)	KD (μM)
cSLAM	2.5 × 104	2.0 × 10−1	8.0
cSLAM G71A	6.3 × 103	5.9 × 10−1	93.7
cSLAM N72A	2.1 × 104	5.7 × 10−1	27.1
cSLAM E123A	2.6 × 104	6.4 × 10−1	24.6
cSLAM 5A	1.2 × 104	5.7 × 10−1	47.5

^ak_a, association constant (on rate); k_d, dissociation constant (off rate); K_D, equilibrium dissociation constant.