Table 2.
Comparison of patient characteristics between hospitalisations for lower respiratory tract infection with and without acute kidney injury
| Hospitalisations with AKI diagnosis (N = 230) (%) |
Hospitalisations without AKI diagnosis (N = 7574) (%) |
P Value | |
|---|---|---|---|
| Age (years) | < 0.001 | ||
| < 65 | 10.9 | 31.4 | |
| 65-74 | 22.2 | 29.2 | |
| 75-84 | 41.7 | 27.9 | |
| ≥ 85 | 25.2 | 11.5 | |
| Sex (Male) | 53.0 | 36.3 | < 0.001 |
| Smoking history | 0.037 | ||
| Non-smoker | 28.7 | 37.7 | |
| Ex-smoker | 59.6 | 53.4 | |
| Current smoker | 11.3 | 8.6 | |
| Missing | 0.4 | 0.3 | |
| Co-diagnosis of COPD | 60.4 | 50.0 | 0.002 |
| Outpatient eGFR (mL/min/1.73 m2) | <0.001 | ||
| > 60 | 33.0 | 53.8 | |
| 45-60 | 17.4 | 11.0 | |
| 30-45 | 21.3 | 4.2 | |
| 15-30 | 10.0 | 1.3 | |
| No measurement | 18.3 | 29.8 | |
| History of AKI | 20.4 | 4.4 | < 0.001 |
| Chronic conditions | |||
| Heart failure | 19.6 | 9.0 | < 0.001 |
| Cirrhosis | 0.9 | 0.6 | 0.638 |
| Diabetes | 26.1 | 13.1 | < 0.001 |
| Dementia | 4.8 | 2.9 | 0.107 |
| Prostatic hypertrophy | 17.0 | 7.5 | < 0.001 |
| Drugs with nephrotoxic potential | |||
| NSAIDs | 28.3 | 22.5 | 0.038 |
| Aminoglycoside nebuliser | 1.3 | 0.1 | 0.001 |
| Aminoglycoside injection | 1.3 | 0.7 | 0.227 |
| ACEI or ARBs | 35.2 | 21.9 | < 0.001 |
| Diuretics | 44.8 | 29.5 | < 0.001 |
| Sepsis diagnosis | 12.2 | 1.0 | < 0.001 |
ACEI, angiotensin converting enzyme inhibitor; AKI, acute kidney injury; ARB, angiotensin II receptor blocker; COPD, chronic obstructive pulmonary disease; eGFR, estimated glomerular filtration rate; NSAIDs, non-steroidal anti-inflammatory drugs