Table 3.
Multivariable logistic regression analysis for factors associated with diagnosis of acute kidney injury
| Adjusted odds ratioa | 95 % confidence interval | |
|---|---|---|
| Age (years old) | ||
| <65 | Reference | |
| 65-74 | 1.49 | 0.87 – 2.57 |
| 75-84 | 2.26 | 1.34 – 3.80 |
| ≥85 | 2.64 | 1.48 – 4.68 |
| Sex (Male/Female) | 1.75 | 1.23 – 2.49 |
| Smoking history | ||
| Non-smoker | Reference | |
| Ex-smoker | 0.94 | 0.65 – 1.35 |
| Current smoker | 1.50 | 0.87 –2.58 |
| Co-diagnosis of COPD (Yes/No) | 1.18 | 0.85 – 1.63 |
| Outpatient eGFR (mL/min/1.73 m2) | ||
| > 60 | Reference | |
| 45-60 | 2.44 | 1.54 – 3.86 |
| 30-45 | 7.42 | 4.46 – 12.34 |
| 15-30 | 10.73 | 5.35 – 21.53 |
| No measurement | 1.55 | 0.99 – 2.42 |
| History of AKI (Yes/No) | 1.93 | 1.23 – 3.03 |
| Chronic conditions (Yes/No) | ||
| Heart failure | 1.06 | 0.69 – 1.63 |
| Cirrhosis | 1.50 | 0.25 – 9.16 |
| Diabetes | 1.38 | 0.94 – 2.02 |
| Dementia | 0.92 | 0.44 – 1.93 |
| Prostatic hypertrophy | 1.28 | 0.79 – 2.08 |
| Drugs with nephrotoxic potential (Yes/No) | ||
| NSAIDs | 0.95 | 0.66 – 1.36 |
| Aminoglycosides nebuliser | 6.15 | 0.43 – 87.59 |
| Aminoglycosides injection | 3.90 | 0.98 – 15.58 |
| ACEI or ARBs | 1.34 | 0.94 – 1.92 |
| Diuretics | 1.19 | 0.84 – 1.70 |
| Sepsis diagnosis (Yes/No) | 18.32 | 10.04 – 33.41 |
ACEI, angiotensin converting enzyme inhibitor; AKI, acute kidney injury; ARB, angiotensin II receptor blocker; COPD, chronic obstructive pulmonary disease; eGFR, estimated glomerular filtration rate; NSAIDs, non-steroidal anti-inflammatory drugs
aAdditionally adjusted by financial year of hospitalisation