Figure 6.

The effects of levodopa administration on writing related network. The effects of levodopa administration on writing related network connectivity in Parkinson’s disease patients with consistent (A) and progressive micrographia (B). Post hoc t-test, P < 0.05, FWE corrected. Red and green colours indicate increased and decreased connectivity in the free writing ON condition compared to the free writing condition, respectively. T-values of these connections are shown on each connection. Blue dashed line indicates disconnection among cerebellum, pre-SMA and rCMA. L = left; R = right; APu = anterior putamen; CB = cerebellum; PPu = posterior putamen; pre-SMA = rostral supplementary motor area; SMA = caudal supplementary motor area; Th = thalamus.