Table 4.

Results of in-vitro release studies of Naproxen.

Formulation code	Lag time in hours (i.e. time taken for less than 10% of Naproxen release)	Mean % cumulative drug release at the end of 8 h	Mean % cumulative drug release at the end of 12 h
F1	2.01 ± 0.89	99.52 ± 0.82	–
F2	2.12 ± 0.70	99.87 ± 0.90	–
F3	2.36 ± 0.93	98.39 ± 0.44	99.86 ± 0.94+
F4	2.42 ± 0.80	90.16 ± 0.76	99.73 ± 0.52
F5	2.03 ± 0.66	99.95 ± 0.59	–
F6	2.20 ± 1.07	99.80 ± 1.14	–
F7	2.08 ± 0.59	99.74 ± 0.78	–
F8	2.25 ± 1.15	98.60 ± 0.61	99.46 ± 0.70+
F9	2.34 ± 0.61	97.10 ± 0.98	99.85 ± 0.83+
F10	2.40 ± 0.98	91.92 ± 0.39	99.90 ± 0.95+
F11	2.03 ± 0.74	99.97 ± 0.89∗	–
F12	2.06 ± 0.96	98.61 ± 0.71∗	–
F13	2.10 ± 0.80	99.57 ± 0.40∗	–
F14	2.15 ± 0.79	99.86 ± 0.95∗	–
F15	2.09 ± 0.94	99.10 ± 0.62∗	–
F16	2.14 ± 0.67	99.47 ± 0.37	–
F17	2.34 ± 1.10	99.69 ± 1.18	–
F18	2.45 ± 0.97	92.59 ± 0.47	99.38 ± 0.69
F19	2.11 ± 0.74	99.94 ± 1.07∗	–
F20	2.27 ± 0.90	99.47 ± 0.36	–
F21	2.32 ± 0.96	99.20 ± 0.54	–
F22	2.24 ± 0.79	99.74 ± 0.86	–
F23	2.26 ± 0.88	98.26 ± 0.73	99.88 ± 0.92+
F24	2.21 ± 0.94	99.15 ± 0.66	–

Note: ^∗Mark indicates that the Naproxen was released before 8 h.

⁺Mark indicates that the Naproxen was released before 12 h.