Table 2.
Percent of drug loading (DL), cell recovery (CR), hemoglobin release (HbR), pravastatin release (PR-R) of PR–CNG–ER and PR-ER as well as hemolysis percent (Hem), zeta potential (ZP), size distribution (SD) of UER, SH-ER, PR–CNG–ER and PR-ER.
| Parameter | UER | SH-ER | PR–CNG–ER | PR-ER |
|---|---|---|---|---|
| DL (%) | – | – | 36.85 ± 4.37 | 31.54 ± 3.62 |
| CR (%) | – | 58.21 ± 4.81 | 66.82 ± 5.42 | 60.32 ± 6.30 |
| HbR48h (%) | – | – | 90.13 ± 8.95 | 96.23 ± 7.52 |
| PR-R 48h (%) | – | – | 83.74 ± 7.62 | 93.34 ± 8.73 |
| Hem. (%) | 11.33 ± 0.92 | 35.32 ± 4. 21a | 24.97 ± 3.21a | 27.01 ± 2.82a |
| ZP (mV) | −14.82 ± 1.24 | −11.34 ± 0.65 | −10.83 ± 1.01a | −14.28 ± 1.05 |
| SD (μm) | 5.713 ± 0.54 | 5.254 ± 0.49 | 4.165 ± 0.3a | 5.269 ± 0.56 |
Data represented as mean ± SD, (N = 6).
a
Indicated when a significant change was observed.