Table 5. MLE markers, within confinement versus prior to confinement a .
| MLE marker (units) | Time point | N (within-) | N (prior-) | Mean difference b (95% CI) |
|---|---|---|---|---|
| Char line (mm) | Week 0 | 35 | 35 | 0.36 (−1.23, 1.95) |
| Week 12 | 34 | 33 | −0.51 (−2.13, 1.12) | |
| Week 24 | 34 | 32 | −0.32 (−1.97, 1.32) | |
| Nicotine (mg/cigarette) | Week 0 | 31 | 29 | 0.063 (−0.091, 0.216) |
| Week 12 | 30 | 29 | 0.055 (−0.100, 0.211) | |
| Week 24 | 27 | 26 | 0.163 (0.0004, 0.326) c | |
| Nicotine (mg/day) | Week 0 | 31 | 29 | −1.25 (−5.27, 2.78) |
| Week 12 | 30 | 29 | −0.90 (−4.99, 3.18) | |
| Week 24 | 27 | 26 | 2.47 (−1.80, 6.75) | |
| Tar (mg/cigarette) | Week 0 | 31 | 29 | 0.35 (−1.92, 2.62) |
| Week 12 | 30 | 29 | 1.02 (−1.28, 3.32) | |
| Week 24 | 27 | 26 | 2.36 (−0.05, 4.77) | |
| Tar (mg/day) | Week 0 | 31 | 29 | −22.9 (−80.1, 34.3) |
| Week 12 | 30 | 29 | −13.7 (−71.7, 44.3) | |
| Week 24 | 27 | 26 | 28.3 (−32.4, 89.0) |
MLE, mouth level exposure.
a
Ultra-low machine yield tobacco-burning cigarette group only, per-protocol sample.
b
Least squares mean from ANOVA; difference calculated as within confinement minus prior to confinement.
c
p < 0.05.