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. 2015 Feb 17;48(1):398–402. doi: 10.4143/crt.2014.254

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Copyright © 2016 by the Korean Cancer Association

This is an Open-Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Fig. 1. — (A) Computed tomography scan of the chest showing a solid nodule with a speculated margin (arrow) measuring 1.5-cm in size in the lower lobe of the right lung. (B) Anaplastic lymphoma kinase (ALK) immunohistochemical staining showing cytoplasmic staining of tumor cells (×100). (C) Fluorescence in situ hybridization assay of ALK showing ALK genomic rearrangement by split 5'- and 3'-probe signals (arrows). (D-F) Hematoxylin and eosin staining showing adenocarcinoma (D, ×100), and a mixture of acinar pattern (E, ×200) and solid pattern (F, ×200).