Table 2.
Pearson’s correlation and logistic regression analyses of predictive factors for lymph node metastases
| Variable | Univariate analysis |
Multivariate analysis |
|||
|---|---|---|---|---|---|
| Spearman’s ρ | p-value | Adjusted OR | 95% CI | p-value | |
| Age | -0.144 | 0.010 | - | - | - |
| Tumour size | 0.100 | 0.078 | - | - | - |
| T stage | 0.107 | 0.058 | - | - | - |
| Multiplicity | 0.068 | 0.232 | - | - | - |
| Histologic grade | -0.131 | 0.021 | - | - | - |
| Lymphatic invasion | 0.331 | < 0.001 | 4.613 | 2.736-7.778 | < 0.001 |
| Venous invasion | 0.164 | 0.004 | - | - | - |
| Estrogen receptor | 0.112 | 0.047 | - | - | - |
| Progesterone receptor | 0.135 | 0.019 | - | - | - |
| Ki-67 ≥ 20% | -0.136 | 0.016 | 0.551 | 0.323-0.938 | 0.028 |
| MembCA12 | 0.188 | 0.001 | - | - | - |
| CytoCA12 | 0.165 | 0.004 | - | - | - |
| StromaCA9 | 0.187 | 0.001 | 2.601 | 1.506-4.492 | 0.001 |
OR, odds ratio; CI, confidence interval; MembCA12, membrane staining by carbonic anhydrase (CA) 12; CytoCA12, cytoplasmic staining by CA12; StromaCA9, staining by CA9 in stromal cells.