Table 1.
Clinical characteristics according to radiotherapy technique
| Characteristic | 3D-CRT (n=48) | IMRT (n=29) | p-value |
|---|---|---|---|
| Age (yr) | 62 (44-72) | 59 (40-80) | 0.744 |
| Sex | |||
| Male | 35 (72.9) | 18 (62.1) | 0.390 |
| Female | 13 (27.1) | 11 (37.9) | |
| Smoking history | 34 (70.8) | 17 (58.6) | 0.272 |
| FEV1 (L) | 2.49 (1.17-3.90) | 2.50 (1.46-3.71) | 0.791 |
| ECOG performance | |||
| 0 | 10 (20.8) | 6 (20.7) | 0.988 |
| 1 | 38 (79.2) | 23 (79.3) | |
| Primary site | |||
| Upper-middle lobes | 39 (81.3) | 13 (44.8) | 0.001 |
| Lower lobes | 9 (18.7) | 16 (55.2) | |
| Histology | |||
| Adenocarcinoma | 31 (64.6) | 22 (75.9) | 0.053 |
| Squamous cell carcinoma | 15 (31.2) | 3 (10.3) | |
| Others | 2 (4.2) | 4 (13.8) | |
| Tumor size (cm) | 3.8 (1.3-12.2) | 3.7 (1.0-9.2) | 0.785 |
| Clinical T classification | |||
| cT1-2 | 34 (70.8) | 23 (79.3) | 0.411 |
| cT3-4 | 14 (29.2) | 6 (20.7) | |
| N3 involvement region | |||
| Contralateral mediastinum | 29 (60.4) | 7 (24.1) | 0.002 |
| Supraclavicular | 26 (54.2) | 24 (82.8) | 0.011 |
Values are presented as median (range) or number (%). 3D-CRT, three-dimensional conformal radiotherapy; IMRT, intensity-modulated radiotherapy; FEV1, forced expiratory volume in 1 second; ECOG, Eastern Cooperative Oncology Group.