Table 2.

Comparison by cystoscopy modality for detection of NMIBC

Variable	Total	Microscopic hematuria	Gross hematuria	Prior NMIBC
WLC (per case)
Sensitivity	94.12	100	100	83.33
Specificity	86.96	82.35	90.91	88.89
PPV	72.73	50	88.89	71.43
NPV	97.56	100	100	94.12
Accuracy	88.89	85	94.74	87.5
NBI (per case)
Sensitivity	100	100	100	100
Specificity	50***	52.94	63.64	38.89**
PPV	42.50	27.27	66.67	35.29
NPV	100	100	100	100
Accuracy	63.49	60	78.95	54.17
WLC (per biopsy)
Sensitivity	90.48	100	100	75
Specificity	62.22	50	50	78.95
PPV	52.78	30	62.50	60
NPV	93.33	100	100	88.24
Accuracy	71.21	58.82	72.73	77.78
NBI (per biopsy)
Sensitivity	100	100	100	100
Specificity	15.56***	14.29	25	10.53***
PPV	35.59	20	52.63	32
NPV	100	100	100	100
Accuracy	42.42	29.41	59.09	37.04

Values are presented as percentage. NMIBC, nonmuscle invasive bladder cancer; WLC, white light cystoscopy; PPV, positive predictive value; NPV, negative predictive value; NBI, narrow band imaging.

^**p < 0.01, in comparison with WLC,

^***p < 0.001, in comparison with WLC.