Table 2.
Response after chemoradiotherapy according to FGFR4 Gly388Arg polymorphism
| Genotype | Responder (CR+PR, n=210) | Non-responder (SD+PD, n=34) | p-value |
|---|---|---|---|
| G/G (n=94) | 86 (91.5) | 8 (8.5) | 0.090 |
| G/A (n=110) | 89 (80.9) | 21 (19.1) | |
| A/A (n=40) | 35 (87.5) | 5 (12.5) | |
| G/G (n=94) | 86 (91.5) | 8 (8.5) | 0.038 |
| G/A+A/A (n=150) | 124 (82.7) | 26 (17.3) |
Values are presented as number (% of each gene group). FGFR4, fibroblast growth factor receptor 4; CR, complete response; PR, partial response; SD, stable disease; PD, progressive disease.