Table 2.
Treatments at recurrence
| Variable | GBM | Grade III | Total |
|---|---|---|---|
| Treatment at recurrence | |||
| Combined modality | 12 (63.2) | 7 (36.8) | 19 |
| Radiotherapy alone | 1 (16.7) | 5 (83.3) | 6 |
| Radiotherapy | |||
| Median volume of recurrent disease | |||
| < 35 cm3 | 8 (61.5) | 5 (38.5) | 13 |
| ≥ 35 cm3 | 5 (41.7) | 7 (58.3) | 12 |
| Dose prescription | |||
| 25 Gy/5 fractions | 13 (54.1) | 11 (45.9) | 24 |
| 50 Gy/10 fractions | 0 | 1 (100) | 1 |
| Chemotherapy | |||
| Temozolomide rechallenge | 5 (83) | 1 (17) | 6 |
| Bevacizumab | 1 (100) | 0 | 1 |
| ACNU | 0 | 1 (100) | 1 |
| Fotemustine | 7 (70) | 3 (30) | 10 |
| PC scheme | 0 | 1 (100) | 1 |
| Surgery | |||
| Subtotal resection | 3 (50) | 3 (50) | 6 |
| Complete resection | 2 (40) | 3 (60) | 5 |
Values are presented as number (%). GBM, glioblastoma; ACNU, adjuvant chemotherapy with nimustine; PC, paclitaxel and carboplatin.