Table 3.

Overall survival and progression-free survival stratified by histology and parameters

Variable	1-Year OS	2-Year OS	p-value	1-Year PFS	2-Year PFS	p-value
Diagnosis
GBM	61	35	0.29	62	35	0.32
Grade III	89	66		83	18
Results by EOR at diagnosis
Complete resection	73	59	< 0.01	73	39	< 0.01
Partial resection	86	43		71	0
Results by MGMT
Methylated	100	83	0.05	100	83	0.08
Un-methylated	67	67		67	33
Results by recurrent tumor volume
≤ 50 cm3	-	56	0.26	-	42	0.1
> 50 cm3	-	33		-	11
Results by treatment approach
Combined	83	51	0.89	74	32	0.94
RT alone	73	0		67	0

Values are presented as percentage. GBM, glioblastoma; EOR, extent of resection; MGMT, methylguanine-DNA methyltransferase; RT, radiotherapy.