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Expression of pFOXO1, SIRT1, and HIF-1α in human GC specimens
| Variable | pFOXOl |
p-value | SIRT1 |
p-value | ||
|---|---|---|---|---|---|---|
| Positive | Negative | Positive | Negative | |||
| Total | 359 (77) | 108 (23) | 178 (38) | 293 (62) | ||
| SIRT1 | ||||||
| Positive | 152 (86) | 25 (14) | < 0.001 | - | - | - |
| Negative | 207 (71) | 83 (29) | - | - | ||
| HIF-1α | ||||||
| Positive | 100 (93) | 8 (7) | < 0.001 | 68 (64) | 39 (36) | < 0.001 |
| Negative | 260 (72) | 101 (28) | 110 (30) | 254 (70) | ||
Values are presented as number (%). pFOXO1, phospho-FOXO1Ser256; HIF-1α, hypoxia inducible factor-1α; GC, gastric cell.
