Table 1.
Body\organ weights of female B6C3F1 mice dermally exposed to triclosan for 28 days.
| Triclosan | |||||
|---|---|---|---|---|---|
| Parameter | 0% | 0.75% | 1.5% | 3.0% | |
| Body weight | (g) | 20.52±0.33 | 20.04±0.35 | 20.32±0.64 | 20.72±0.32 |
| Kidney weight | (mg) | 249±7 | 256±9 | 237±8 | 248±8 |
| % BW | 1.22±0.04 | 1.28±0.03 | 1.17±0.04 | 1.20±0.03 | |
| Spleen weight | (mg) | 65±3 | 67±2 | 71±2 | 76±3*# |
| % BW | 0.32±0.01 | 0.33±0.01 | 0.35±0.01 | 0.37±0.02# | |
| Thymus weight | (mg) | 38±4 | 44±7 | 42±3 | 39±3 |
| % BW | 0.19±0.02 | 0.22±0.04 | 0.21±0.02 | 0.19±0.01 | |
| Liver weight | (mg) | 896±18 | 939±48 | 999±45* | 1058±133**# |
| % BW | 4.37±0.06 | 4.68±0.16 | 4.94±0.15* | 5.11±0.12**# | |
BW, body weight.
Values are expressed as mean±SE for each group.
Significantly different from acetone control at *p<0.05 or **p<0.01.
Linear Trend; #p<0.05.