. 2016 Jan 20;11(1):e0146684. doi: 10.1371/journal.pone.0146684

Table 2. ROI morphometric values (μ ± σμ).

		JMD	HCY	f-value (df = 1.63)	p-value	AMD	HCO	f-value (df = 1.42)	p-value
Average cortical thickness (mm)	V1 anterior	1.653 ± 0.036	1.682 ± 0.037	0.029	0.866	1.527 ± 0.033	1.594 ± 0.042	3.447	0.070
	V1 posterior	1.775 ± 0.024	1.851 ± 0.031	4.227	0.044 ^*	1.756 ± 0.041	1.832 ± 0.034	2.700	0.108
	V2 anterior	1.965 ± 0.035	2.029 ± 0.029	1.834	0.181	1.804 ± 0.022	1.865 ± 0.035	4.078	0.050 ^*
	V2 posterior	1.888 ± 0.021	1.991 ± 0.023	11.400	0.001 ^*	1.809 ± 0.028	1.929 ± 0.028	8.351	0.006 ^*
Mean Curvature (mm^-1)	V1 anterior	0.162 ± 0.003	0.168 ± 0.003	2.500	0.119	0.179 ± 0.003	0.184 ± 0.009	3.297	0.077
	V1 posterior	0.186 ± 0.002	0.185 ± 0.002	0.002	0.963	0.188 ± 0.005	0.194 ± 0.007	1.947	0.170
	V2 anterior	0.170 ± 0.002	0.173 ± 0.002	1.323	0.254	0.173 ± 0.002	0.174 ± 0.003	1.282	0.264
	V2 posterior	0.181 ± 0.002	0.179 ± 0.001	0.696	0.407	0.181 ± 0.004	0.186 ± 0.005	1.495	0.234
Surface area (mm²)	V1 anterior	2130.29 ± 74.94	2352.67 ± 81.51	4.145	0.046 ^*	2185.38 ± 90.65	2060.50 ± 95.69	3.607	0.064
	V1 posterior	4753.91 ± 123.91	5256.55 ± 149.70	6.598	0.013 ^*	4408.08 ± 169.35	4770.41 ± 212.15	0.160	0.691
	V2 anterior	4203.88 ± 124.91	4502.91 ± 104.34	3.225	0.077	4189.17 ± 162.17	4037.82 ± 153.63	3.190	0.081
	V2 posterior	7998.18 ± 151.94	8613.58 ± 204.26	5.718	0.020 ^*	7688.42 ± 252.08	7795.09 ± 273.75	0.231	0.633
Grey matter volume (mm³)	V1 anterior	3590.97± 138.45	4035.21 ± 166.09	3.516	0.065	3455.33 ± 140.77	3391.14 ± 192.45	0.381	0.540
	V1 posterior	9682.56 ± 229.84	11068.33 ± 311.69	11.898	0.001 ^*	8931.46 ± 312.43	10024.64 ± 347.80	2.205	0.145
	V2 anterior	8764.59 ± 280.49	9750.70 ± 272.10	5.890	0.018 ^*	8117.08 ± 266.15	8053.18 ± 349.58	0.269	0.607
	V2 posterior	17325.68 ± 331.33	19448.18 ± 485.69	12.028	0.001 ^*	16031.33 ± 446.11	17215.18 ± 564.76	0.811	0.373

Average cortical thickness, mean curvature, surface area and grey matter volume were extracted from the ROIs V1 anterior, V1 posterior, V2 anterior and V2 posterior. Mean values and standard error of the mean are presented for each parameter and each ROI (f-values, degrees of freedom and p-values are given).

ROI—region of interest; μ - mean; σμ - standard error of the mean; df–degrees of freedom; JMD—juvenile macular degeneration; HCY—healthy controls young (age-matched to JMD); AMD—age-related macular degeneration; HCO—healthy controls old (age-matched to AMD).

* Significant difference between the patients group and the respective age-matched control group (p < 0.05).