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. Author manuscript; available in PMC: 2016 Jan 20.
Published in final edited form as: Cell Rep. 2015 Dec 10;13(11):2553–2564. doi: 10.1016/j.celrep.2015.11.043

Figure 4. Footprints of C9 and IM-CKV063 span two neighboring E2.

Figure 4

“Roadmaps” of the footprints of C9 (A) or IM-CKV063 (B) Fabs on the VLP surface at q3 spike. To differentiate between amino acids in three different q3-fold related subunits, their identity is defined as the amino acid sequence number in E1 + 2000, 3000, and 4000, and in E2 + 2500, 3500, and 4500 individually. The surface is colored according to radial distance from the center of the VLP. Domain As of three E2 are bounded by black, grey and purple lines respectively. B domains of E2 are bounded by white lines. The β-ribbon connectors of E2 are bounded by magenta lines. The footprints of the Fabs on the VLP surface are outlined in yellow. The footprint of a single Fab is boxed in white and an enlarged image of the boxed area is shown on the right. E2-W64 is labeled with white star.