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. 2016 Jan 20;12(1):e1005777. doi: 10.1371/journal.pgen.1005777

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© 2016 Lomada et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 4 — (A) Representative FACS plots show percentage of MHCII^loCD80^lo and MHCII^hiCD80^hi mTECs. (B) Bar graph shows number (mean ± SD) of MHCII^lo and MHCII^hi mTECs in K5.Stat3C and control thymi (n = 5 each). (C) FACS plots show percentage of MHCII^hiAire⁺ mTECs. (D) Bar graph shows number (mean ± SD) of MHCII^hiAire⁺ mTECs (n = 5). (E) IHC stains show abundant K14+ and Aire+ mTECs in K5.Stat3C thymi. Scale bar: 200μm. (F) The frequency of involucrin+ mTECs is not increased in K5.Stat3C thymi. Scale bar: 100μm. (G) IHC stains show K8 expressing cTECs and CD11c expressing DCs. Scale bar: 200μm. *P<0.05 (Student’s paired t-test).