Table 1. Quantification of BBB permeability by in vivo imaging.
Mouse | Genotype | Surgery | Δ[30–0 min] |
---|---|---|---|
1 | WT | Sham | -1.4 |
2 | ΔEndoMyD88 | Sham | -3.9 |
3 | WT | CLP | 15.8 |
4 | ΔEndoMyD88 | CLP | 8.4 |
5 | ΔEndoMyD88 | CLP | 10.6 |
6 | ΔEndoMyD88 | CLP | 17.1 |
Extravasation index was calculated as described in Methods.