Table 3. Means and standard deviations on each of the speech and pause measures for each group.
| ALS | FTD | Controls (N = 32) | |||||
|---|---|---|---|---|---|---|---|
| ALS-M (N = 27) | ALS-R (N = 25) | ALS-B (N = 21) | ALS-RB (N = 10) | FTD-BV (N = 9) | FTD-PNFA (N = 9) | ||
| Speaking rate (WPM) | 156.63 ±27.96 c,d,f | 150.02 ±24.87** c | 104.43 ±26.27*** a,b,e | 123.45 ±38.73*** a | 140.45 ±48.88* c | 118.57 ±32.15*** a | 176.83 ±20.93 |
| Articulatory rate (SPM) | 268.53 ±37.64c,f | 267.93 ±37.80c,f | 176.30 ±38.90***a,b,d,e | 234.17 ±67.32***c | 256.32 ±47.32c | 219.04 ±35.34***a,b | 285.79 ±29.85 |
| Mean phrase duration (sec) | 2.85 ±0.85 | 2.31 ±0.93 ** | 2.91 ±0.63 | 2.05 ±0.50** | 2.87 ±1.95 | 2.08 ±0.69** | 3.19 ±0.55 |
| CV phrase† | 0.67 ±0.17*** | 0.59 ±0.10*** | 0.57 ±0.19*** | 0.57 ±0.16* | 0.53 ±0.23 | 0.61 ±0.17** | 0.39 ±0.11 |
| Pause time (sec) | 8.19 ±4.21 | 9.62 ±7.45 | 12.36 ±3.56* | 15.69 ±8.25** | 17.10 ±21.39*** | 15.82 ±12.76** | 5.19 ±1.50 |
| # of Pauses | 11.11 ±4.16 | 13.60 ±8.44 | 16.90 ±4.88** | 19.20 ±7.44** | 19.56 ±21.62** | 20.11 ±10.18**a | 8.44 ±1.98 |
| % Pause time | 20.06 ±7.11 | 23.17 ±6.51** | 19.94 ±5.61 | 27.89 ±6.47*** | 25.91 ±19.06 ** | 26.18 ±12.93** | 15.07 ±3.15 |
| Mean pause duration (sec)† | 0.72 ±0.17 | 0.72 ±0.17 | 0.71 ±0.16 | 0.79 ±0.20 | 0.76 ±0.20 | 0.73 ±0.32 | 0.62 ±0.12 |
| CV pause | 0.38 ±0.18 | 0.34 ±0.20 | 0.43 ±0.13** | 0.45 ±0.18* | 0.50 ±0.28** | 0.44 ±0.18 | 0.26 ±0.08 |
ALS: M = Mild, R = Respiratory, B = Bulbar, RB = Respiratory-Bulbar; FTD: FTD-BV = Behavioral variant FTD, FTD-PNFA = Non-fluent primary progressive aphasia, CV = coefficient of variation, WPM = words per minute, SPM = syllables per minute. Asterisks denote significantly impaired relative to normal controls at
*p<0.05;
**p<0.01;
***p<0.001. Superscript letters denote significantly impaired relative to the
a mild,
b respiratory,
c bulbar,
d respiratory-bulbar,
e FTD-BV, and
f FTD-PNFA at p<0.05.
†Tested with non-parametric statistics.