Table 2.
Sensitivity analysis based on the largest group of datasets (daily throughout and rifampicin throughout)
| Criteria | Cut off | Datasets | Success | Failed | Relapsed | Defaulted |
|---|---|---|---|---|---|---|
| Study size | Small <166 | 9 | 0.91 (0.81–0.99) | 0.03 (0.00–0.10) | 0.02 (0.00–0.08) | 0.03 (0.00–0.10) |
| Big ≥166 | 10 | 0.90 (0.82–0.96) | 0.04 (0.00–0.08) | 0.01 (0.00–0.03) | 0.05 (0.01–0.11) | |
|
| ||||||
| Year of publication | Before 1999 | 8 | 0.98 (0.97–0.99) | 0.01 (0.00–0.02) | 0.01 (0.01–0.02) | 0.00 (0.00–0.00) |
| 1999 and after | 11 | 0.84 (0.76–0.91) | 0.05 (0.01–0.10) | 0.01 (0.00–0.03) | 0.09 (0.04–0.15) | |
|
| ||||||
| Country | African or African with other settings purely non-African | 4 | 0.92 (0.84–0.98) | 0.02 (0.00–0.07) | 0.01 (0.00–0.05) | 0.04 (0.00–0.10) |
| 15 | 0.89 (0.80–0.97) | 0.04 (0.00–0.10) | 0.01 (0.00–0.04) | 0.05 (0.00–0.12) | ||
|
| ||||||
| Monitored therapy | Fully | 6 | 0.90 (0.74–1.00) | 0.04 (0.00–0.15) | 0.02 (0.00–0.10) | 0.04 (0.00–0.16) |
| Partly/not at all/unspecified | 13 | 0.90 (0.83–0.95) | 0.04 (0.00–0.08) | 0.01 (0.00–0.03) | 0.05 (0.01–0.10) | |