Table 4.

Mean Scores of Lupus Nephritis Clinical Indices in Relation to Kidney Damage ^*

Clinical Measures of Activity		SLEDAI-R	BILAG-R	SLICC-RAS
Histological Measure of Damage
NIH CI Score	0 (N=34)	7.83 ± 0.83	10.89 ± 0.50	4.26 ± 0.92
	> 0 (N=36)	10.82 ± 0.85	10.82 ± 0.51	7.69 ± 0.95
	P-value	0.014	NS	0.012
SDI-R¶	0 (N=68)	8.32 ± 0.62	10.66 ± 0.37	5.18 ± 0.64
	> 0 (N=14)	11.14 ± 1.36	10.86 ± 0.81	11.45 ± 1.52
	P-valueŦ	0.062	0.823	0.000
Chronic Kidney Disease	Stage 1 (N=54)	8.00 ± 0.66†	10.36 ± 0.42	5.64 ± 0.78
	Stage 2 (N=16)	8.63 ± 1.22†	10.81 ± 0.76	4.80 ± 1.38
	Stage 3 (N=6)	12.00 ± 1.99	12.00 ± 1.24	9.83 ± 2.18
	Stage 4 or 5 (N=5)	15.20 ± 2.18	12.00 ± 1.36	10.20 ± 2.39

^*Values are means (95%CI)

^ŦP-values based on t-test comparing means of Lupus Nephritis Clinical Indices for low versus high NIH CI Score, with cut-offs defined in the table

^¶SDI-R: Systemic Lupus International Collaborating Clinics-Damage Index (score = 0 to maximum of 5). Based on glomerular filtration rate (GFR) < 50%, presence of end stage renal disease and proteinuria > 3.5 gram/day

^ŦŦCKD Stage 1: normal GFR; Stage 2: GFR 60–89 ml/min/1.73m²; Stage 3: GFR 30–59 ml/min/1.73m²; Stage 4: GFR 15–29 ml/min/1.73m²; Stage 5: GFR <15 ml/min/1.73m²

^†Means are statistically different from that of State 4+5, in post hoc tests after adjusting for multiple comparison using a Bonferroni’s method.