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. 2016 Jan 21;5:59. doi: 10.1186/s40064-016-1700-0

Table 6.

Clinical benefit by tumor subtypes and treatment line

Characteristics Clinical benefit
N (%)
P
Triple negative
 Yes 6 (23.1) n.s.
 Not 30 (34.5)
ER/PgR status
 ER and/or PgR positive 28 (33.3) n.s.
 ER and/or PgR negative 12 (41.4)
HER2
 Overexpressed/amplified 6 (46.1) n.s.
 Not overexpressed/amplified 32 (34.8)
Dominant disease site
 Visceral 34 (40) 0.07
 Non visceral 6 (21.4)
Metastatic disease site
 1 5 (27.8) n.s.
 ≥2 35 (36.8)
Number of prior chemotherapy for advanced disease
 2 12 (35.3) n.s.
 ≥3 28 (35.4)