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Microdialysis levels of lactate (median (interquartile range)) in the sagittal sinus and femoral artery doing hemorrhagic shock in pigs. Note that lactate levels increases in both compartments during shock. After re-infusion of blood, lactate levels in the sagittal sinus remain at a high level throughout the monitoring period. In contrast, the lactate levels in the femoral artery decline to a near-normal level. S indicates the start of bleeding to achieve a MAP of 40 mmHg
