Table 1.
General physiological and biochemical variables doing hemorrhagic shock
| Elapsed time (min) | MAP (mmHg) | ICP (mmHg) | CPP (mmHg) | PbtO2 (kPa) | PaO2 (kPa) | PaCO2 (kPa) |
| S −60 | 102 (96–111) | 7 (3–11) | 95 (90–106) | 16 (14–27) | 25 (24–27) | 6.0 (5.2–6.1) |
| S | 77 (73–99) | 8 (2–12) | 72 (64–93) | 22 (16–31) | 24 (23–25) | 5.7 (5.4–6.0) |
| 0 | 40 (40–40) | 8 (6–8) | 32 (28–34) | 13 (7–18) | 24 (23–25) | 5.6 (5.5–5.6) |
| 30 | 37 (33–39) | 5 (1–9) | 29 (29–31) | 5 (2–8) | 25 (25–26) | 5.9 (5.2–6.5) |
| 60 | 34 (32–36) | 5 (0–8) | 29 (28–31) | 2 (1–3) | 24 (24–25) | 5.7 (5.2–6.0) |
| 90 | 31 (31–33) | 6 (0–13) | 32 (25–43) | 1 (1–2) | 26 (26–28) | 5.0 (4.6–7.2) |
| 120 | 59 (46–84) | 17 (13–22) | 51 (38–62) | 3 (1–4) | 25 (24–26) | 5.6 (4.5–6.3) |
| 150 | 60 (58–65) | 19 (14–28) | 46 (46–47) | 11 (1–21) | 22 (22–24) | 6.5 (5.6–7.3) |
| 180 | 63 (61–99) | 27 (20–34) | 42 (41–65) | 1 (1–9) | 23 (22–23) | 5.1 (4.6–5.7) |
| 210 | 61 (59–65) | 23 (21–31) | 42 (40–42) | 1 (1–5) | 22 (21–22) | 5.4 (4.8–5.6) |
| 240 | 73 (50–104) | 29 (24–39) | 47 (39–49) | 1 (1–1) | 22 (21–23) | 6.1 (5.4–6.4) |
| Elapsed time (min) | b-Hemoglobin (mM/L) | HR (bpm) | b-Glucose (mM/L) | b-Lactate (mM/L) | b-pH | Diuresis (mL) |
| S −60 | 5.7 (5.3–5.8) | 78 (75–84) | 6.8 (6.4–7.1) | 1.5 (1.3–1.7) | 7.43 (7.40–7.47) | 40 (4–106) |
| S | 5.6 (5.2–5.9 | 90 (78–93) | 7.2 (6.8–7.7) | 1.2 (1.0–1.4) | 7.45 (7.43–7.46) | 115 (82–160 |
| 0 | 4.9 (4.7–4.9) | 135 (107–138) | 9.7 (8.9–9.8) | 2.5 (2.0–3.0) | 7.41 (7.41–7.43) | 12 (0–23) |
| 30 | 4.6 (4.5–4.7) | 116 (111–146) | 8.6 (7.7–14.4) | 5.3 (3.7–7.4) | 7.34 (7.32–7.38) | 4 (3–5) |
| 60 | 5.2 (4.9–5.5) | 166 (129–191 | 7.9 (6.2–13.1) | 7.2 (4.7–11.1) | 7.30 (7.25–7.41) | 2 (1–5) |
| 90 | 5.2 (5.2–5.4) | 125 (114–168) | 7.0 (4.8–9.2) | 10.3 (6.0–10.3) | 7.20 (7.18–7.31) | 3 (2–10) |
| 120 | 5.1 (4.6–5.6) | 98 (93–116) | 6.2 (5.2–7.0) | 5.5 (4.4–6.5) | 7.29 (7.21–7.34) | 16 (5–31) |
| 150 | 5.2 (5.1–5.6) | 101 95–120) | 6.4 (4.9–7.6) | 4.8 (3.6–6.9) | 7.20 (7.19–7.24) | 20 (17–25) |
| 180 | 5.5 (5.2–5.8) | 110 (103–113) | 6.5 (5.7–8.5) | 2.5 (2.1–3.7) | 7.43 (7.33–7.50) | 70 (25–70) |
| 210 | 5.5 (5.3–5.7) | 122 (88–128) | 4.5 (3.9–5.4) | 2.1 (1.7–3.3) | 7.43 (7.39–7.43) | 45 (5–45) |
| 240 | 5.8 5.7–5.8) | 17 (105–121) | 5.5 (4.6–6.1) | 2.0 (1.2–3.0) | 7.36 (7.33–7.47) | 18 (5–100) |
Data are expressed as median levels (interquartile range). S indicates the start of bleeding to achieve a MAP of 40 mmHg
MAP mean arterial pressure, ICP intracranial pressure, CPP cerebral perfusion pressure, PbtO 2 brain tissue oxygenation.