Table 2.
Bleeding with Dalteparin vs. Unfractioned Heparin. Adjusted and Unadjusted Rates for all CRI Patients and for Patients Separated by GFR
| All Patients (n = 3186) |
GFR < 30 mL/min (n = 927) |
GFR 30–60 mL/min (n = 2259) |
|
|---|---|---|---|
| Unadjusted HR* (95 % CI) |
0.31 (0.17 – 0.55) |
0.35 (0.11 – 1.15) |
0.32 (0.16 – 0.64) |
| Adjusted HR* (95 % CI) |
0.39 (0.21 – 0.70) |
0.37 (0.11 – 1.22) |
0.42 (0.21 – 0.84) |
Adjusted for: age, sex, Charlson score, history of bleeding, use of warfarin, platelet count, GFR and INR
*Cox-proportional hazards model with major bleeding censored at 10 days after start of treatment