Appendix Table 1.
HEDIS Drugs to Avoid in the Elderly, 2006–2007
| Class | Drugs |
|---|---|
| Antianxiety* | Aspirin–meprobamate |
| Meprobamate | |
|
| |
| Antiemetics | Scopolamine |
| Trimethobenzamide | |
|
| |
| Analgesics* | Ketorolac |
|
| |
| Antihistamines* | APAP/dextromethorphan/diphenhydramine |
| APAP/diphenhydramine/phenylephrine | |
| APAP/diphenhydramine/pseudoephedrine | |
| Acetaminophen–diphenhydramine | |
| Carbetapentane/diphenhydramine/phenylephrine | |
| Codeine/phenylephrine/promethazine | |
| Codeine–promethazine | |
| Cyproheptadine | |
| Dexchlorpheniramine | |
| Dexchlorpheniramine/dextromethorphan/PSE | |
| Dexchlorpheniramine/guaifenesin/PSE | |
| Dexchlorpheniramine/hydrocodone/phenylephrine | |
| Dexchlorpheniramine/methscopolamine/PSE | |
| Dexchlorpheniramine–pseudoephedrine | |
| Dextromethorphan–promethazine | |
| Diphenhydramine | |
| Diphenhydramine/hydrocodone/phenylephrine | |
| Diphenhydramine–magnesium salicylate | |
| Diphenhydramine–phenylephrine | |
| Diphenhydramine–pseudoephedrine | |
| Hydroxyzine hydrochloride | |
| Hydroxyzine pamoate | |
| Phenylephrine–promethazine | |
| Promethazine | |
|
| |
| Antipsychotics, typical | Thioridazine |
|
| |
| Amphetamines | Amphetamine–dextroamphetamine |
| Benzphetamine | |
| Dexmethylphenidate | |
| Dextroamphetamine | |
| Diethylpropion | |
| Methamphetamine | |
| Methylphenidate | |
| Phendimetrazine | |
| Phentermine | |
|
| |
| Barbiturates | Butabarbital |
| Mephobarbital | |
| Pentobarbital | |
| Phenobarbital | |
| Secobarbital | |
|
| |
| Long-acting benzodiazepines* | Amitriptyline–chlordiazepoxide |
| Chlordiazepoxide | |
| Chlordiazepoxide–clidinium | |
| Diazepam | |
| Flurazepam | |
|
| |
| Calcium-channel blockers | Nifedipine† |
|
| |
| Gastrointestinal antispasmodics | Dicyclomine |
| Propantheline | |
|
| |
| Belladonna alkaloids* | Atropine |
| Atropine/chlorpheniramine/hyoscyamine/phenylephrine/scopolamine | |
| Atropine/hyoscyamine/phenobarbital/scopolamine | |
| Atropine–difenoxin | |
| Atropine–diphenoxylate | |
| Atropine–edrophonium | |
| Belladonna | |
| Belladonna/ergotamine/phenobarbital | |
| Butabarbital/hyoscyamine/phenazopyridine | |
| Digestive enzymes/hyoscyamine/phenyltoloxamine | |
| Hyoscyamine | |
| Hyoscyamine/methenam/m-blue/phenyl salicyl | |
|
| |
| Skeletal muscle relaxants* | ASA/caffeine/orphenadrine |
| ASA/carisoprodol/codeine | |
| Aspirin–carisoprodol | |
| Aspirin–methocarbamol | |
| Carisoprodol | |
| Chlorzoxazone | |
| Cyclobenzaprine | |
| Metaxalone | |
| Methocarbamol | |
| Orphenadrine | |
|
| |
| Oral estrogens* | Conjugated estrogen |
| Conjugated estrogen–medroxyprogesterone | |
| Esterified estrogen | |
| Esterified estrogen–methyltestosterone | |
| Estropipate | |
|
| |
| Oral hypoglycemics | Chlorpropamide |
|
| |
| Narcotics (includes combination drugs) | ASA/caffeine/propoxyphene |
| Acetaminophen–pentazocine | |
| Acetaminophen–propoxyphene | |
| Belladonna–opium | |
| Meperidine | |
| Meperidine–promethazine | |
| Naloxone–pentazocine | |
| Pentazocine | |
| Propoxyphene hydrochloride | |
| Propoxyphene napsylate | |
|
| |
| Vasodilators | Dipyridamole† |
| Ergot mesyloid | |
| Isoxsuprine | |
|
| |
| Others‡ | Methyltestosterone |
| Nitrofurantoin and macrocrystals | |
| Nitrofurantoin macrocrystals–monohydrate | |
| Thyroid desiccated | |
APAP = N-acetyl-para-aminophenol; ASA = acetylsalicylic acid; HEDIS = Healthcare Effectiveness Data and Information Set; PSE = pseudoephedrine.
*
Includes combination drugs.
†
Short-acting only.
‡
Includes androgens and anabolic steroids, thyroid drugs, and urinary anti-infectives.