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. 2016 Jan 6;17(1):103–110. doi: 10.3348/kjr.2016.17.1.103

Table 1. Definition of Histologic Grading Scale.

Annulus fibrosus
 Grade 1: normal pattern of fibrocartilage lamellae (U-shaped in posterior aspect and slightly convex in anterior aspect) without ruptured fibers and without serpentine appearance anywhere within annulus
 Grade 2: ruptured or serpentine patterned fibers in less than 30% of annulus
 Grade 3: ruptured or serpentine patterned fibers in more than 30% of annulus
Border between annulus fibrosus and nucleus pulposus
 Grade 1: normal
 Grade 2: minimally Interrupted
 Grade 3: moderate/severe interruption
Cellularity of nucleus pulposus
 Grade 1: normal cellularity with large vacuoles in gelatinous structure of matrix
 Grade 2: slight decrease in number of cells and fewer vacuoles
 Grade 3: moderate/severe decrease (> 50%) in number of cells and no vacuoles
Matrix of nucleus pulposus
 Grade 1: normal gelatinous appearance
 Grade 2: slight condensation of extracellular matrix
 Grade 3: moderate/severe condensation of extracellular matrix