Table 3. Predictors for all composite cerebro-cardiovascular events.
| Univariate analysis | Multivariable analysis | |||||
|---|---|---|---|---|---|---|
| HR | 95% CI | p | HR | 95% CI | p | |
| Age (per 1 year) | 1.05 | 1.03-1.07 | <0.001 | 0.74 | 0.40-1.37 | 0.341 |
| Sex (1=men) | 1.65 | 1.01-2.69 | 0.044 | 1.03 | 1.01-1.06 | 0.020 |
| Hypertension | 1.38 | 0.84-2.25 | 0.203 | 0.89 | 0.53-1.51 | 0.668 |
| Diabetes | 1.51 | 0.93-2.32 | 0.097 | 1.16 | 0.70-1.93 | 0.568 |
| Smoking | 1.48 | 1.13-1.93 | 0.005 | 1.79 | 1.26-2.54 | 0.001 |
| Aspirin use | 2.61 | 1.46-4.68 | 0.001 | 1.55 | 0.82-2.93 | 0.195 |
| Statin use | 2.75 | 1.70-4.46 | <0.001 | 1.96 | 1.17-3.28 | 0.010 |
| Presence of plaque (0, 1) | 4.59 | 2.60-8.10 | <0.001 | 0.31 | 0.06-1.71 | 0.313 |
| IMT (per 1 mm) | 3.64 | 0.95-14.0 | 0.060 | 2.77 | 1.45-5.23 | 0.002 |
| CCA-PSV (per cm/s) | 0.98 | 0.97-0.99 | 0.002 | 0.95 | 0.91-1.00 | 0.032 |
| CCA-EDV (per cm/s) | 0.92 | 0.88-0.95 | <0.001 | 0.99 | 0.97-1.00 | 0.044 |
| CCA-RI | 74.27 | 2.52-2184.91 | 0.013 | 2.07 | 0.04-101.32 | 0.714 |
| ICA-PSV (per cm/s) | 1.01 | 0.99-1.02 | 0.268 | |||
| ICA-EDV (per cm/s) | 0.99 | 0.97-1.03 | 0.806 | |||
| ICA-RI | 8.69 | 0.55-138.21 | 0.126 | |||
HR: hazard ratio, CI: confidence interval, IMT: intima-media thickness, CCA: common carotid artery, PSV: peak systolic velocity, EDV: end-diastolic velocity, RI: resistive index, ICA: internal carotid artery