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. 2015 Jul 14;75(14):1620–1631. doi: 10.1002/pros.23043

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© 2015 The Authors. The Prostate, published by Wiley Periodicals, Inc.

This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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Representative IF images show the heterogeneity of LSC population in naïve and inflamed LSC, in which inflamed LSC reveals intermediate progenitor cells (CK5 and CK8 co‐expressing cells). The upper panel shows CK5⁺ cells (green), no CK8⁺ cells (red), as well as CK5⁻/CK8⁻ cells in naïve LSC. The lower panel shows CK5⁺ (green), CK5⁺/CK8⁺ (green/red) co‐expressing cells, as well as CK5⁻/CK8⁻ cells in inflamed LSC (scale bar: 50 μm).