Figure 4.

Inflammation regulated PSC generates larger spheres, as well as more tubule‐like spheres. A: H&E stained sections showed solid spheres (upper) and tubule‐like spheres (lower) in naïve and inflamed groups (scale bar: 100 μm). B: A bar graph shows diameters of two types of spheres (n = 46 in naïve solid spheres; n = 12 in naïve tubule‐like spheres; n = 17 in inflamed solid spheres; n = 12 in inflamed tubule‐like spheres; error bar = SE; determinations were combined from 3 independent experiments). C: A scanning electron microscope (SEM) image shows weighing of an inflamed prostate sphere. The resonator comprised a sensor and a reference cantilever beam. D: The average density of inflamed spheres (blue bars and curve) is 1.29 g/cm³; naïve spheres (red bars and curve) is 1.1 g/cm³. Specific values of density on x‐axis correspond to the actual numbers of spheres on y‐axis (n = 42 in naïve group; n = 37 in inflamed group; Student's t test, P < 0.0001).