Table 2. Histologic Spectrum of Non-Alcoholic Steatohepatitis in 60 Puerto Rican veterans according to NASH by Brunt.
Total (N = 60) | NASH Assessed by Brunt | P-value | ||
---|---|---|---|---|
+Dx (n=30) | -Dx (n=30) | |||
Steatosis Grade | ||||
< 5% | 6 (10.0) | 1 (3.3) | 5 (16.7) | 0.149 |
5-33% | 14 (23.3) | 5 (16.7) | 9 (30.0) | |
34-66% | 19 (31.7) | 12 (40.0) | 7 (23.3) | |
67-100% | 21 (35.0) | 12 (40.0) | 9 (30.0) | |
Lobular Inflammation | ||||
No Foci | 17 (28.3) | 3 (10.0) | 14 (46.7) | 0.005 |
< 2 Foci | 35 (58.3) | 21 (70.0) | 14 (46.7) | |
2 - 4 Foci | 8 (13.3) | 6 (20.0) | 2 (6.7) | |
Ballooning | ||||
None | 20 (33.3) | 6 (20.0) | 14 (46.7) | 0.061 |
Few Ballooned Cells | 36 (60.0) | 21 (70.0) | 15 (50.0) | |
Many Ballooned Cells | 4 (6.7) | 3 (10.0) | 1 (3.3) | |
Fibrosis | ||||
Absent | 32 (53.3) | 2 (6.7) | 30 (100.0) | <0.001 |
Perisinusoidal/Pericellular Fibrosis | 12 (20.0) | 12 (40.0) | 0 (0) | |
Periportal Fibrosis | 6 (10.0) | 6 (20.0) | 0 (0) | |
Bridging Fibrosis | 8 (13.3) | 8 (26.7) | 0 (0) | |
Cirrhosis | 2 (3.3) | 2 (6.7) | 0 (0) |
Data are shown as frequency percent distribution. P values derived from Fisher's exact test.