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. Author manuscript; available in PMC: 2016 Mar 1.
Published in final edited form as: Sci Signal. 2015 Sep 1;8(392):ra88. doi: 10.1126/scisignal.aaa5157

Fig. 1. TRAF3 inhibits the development of PCs.

Fig. 1

(A) Representative plots from the flow cytometric analysis of cells from the spleen (SP) and bone marrow (BM) of B-Traf3−/− mice and littermate control (LMC) mice. Outlined areas and numbers indicate the percentages of CD138+B220low PCs. Data are representative of four experiments. (B) Percentages (left) and numbers (right) of CD138+B220lowPCs in the spleens and bone marrow of littermate control mice and B-Traf3−/− mice based on data as identified in (A). Each symbol represents a single mouse, and the horizontal line indicates the mean value of each group. (C) Left: Representative wells from the enzyme-linked immunospot (ELISPOT) analysis of ASCs in the spleen and bone marrow of littermate control mice and B-Traf3−/− mice. Right: The numbers of ASCs from the spleen and bone marrow of mice of each strain. Each symbol represents the mean of technical triplicate samples from a single mouse, and the horizontal lines indicate mean values of six mice per group. ***P < 0.001, **P < 0.01, *P < 0.05 by Student’s t test.