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Genetic risk models. q denotes the non-reference allele frequency, γ is the per allele risk.
| Genetic model | Affected genotype frequencies (relative risk) |
|---|---|
| Autosomal dominant | q2 + 2pq (γ) |
| Autosomal recessive | q2 (γ) |
| Additive | q2 (2γ), 2pq (γ) |
| Multiplicative | q2 (γ2), 2pq (γ) |
