Table 4.
Multivariable analysis of the association between earlobe crease and personal history of cardiovascular disease, CoLaus study, Lausanne, 2009–2012
| Adjusted for | Age and gender | Age, gender and BMI | ||
|---|---|---|---|---|
| History of | OR (95 % CI) | P-value | OR (95 % CI) | P-value |
| Any CVD | 1.55 (1.21; 1.98) | <0.001 | 1.47 (1.14; 1.89) | <0.01 |
| Coronary artery disease | 1.85 (1.30; 2.63) | <0.001 | 1.80 (1.26; 2.58) | <0.001 |
| Angina pectoris | 1.28 (0.81; 2.03) | 0.30 | 1.19 (0.74; 1.90) | 0.47 |
| Myocardial infarction | 1.69 (1.08; 2.64) | <0.05 | 1.59 (1.01; 2.51) | <0.05 |
| Stroke | 1.34 (0.84; 2.15) | 0.23 | 1.30 (0.79; 2.11) | 0.30 |
| CABG | 1.70 (0.97; 3.00) | 0.07 | 1.67 (0.93; 2.99) | 0.09 |
| High CVD risk | ||||
| SCORE recalibrated | 1.11 (0.88; 1.41) | 0.37 | 1.10 (0.87; 1.39) | 0.44 |
| Framingham 1998 | 1.09 (0.85; 1.41) | 0.50 | 0.99 (0.76; 1.28) | 0.91 |
| Framingham 1998 r. | 1.15 (0.91; 1.47) | 0.25 | 1.04 (0.81; 1.34) | 0.75 |
Results are expressed as adjusted odds ratio (95 % confidence interval) for presence relative to the absence of ELC. Statistical analysis by logistic regression
BMI body mass index; OR odds ratio; CVD cardiovascular disease; CABG coronary artery bypass graft; high cardiovascular disease risk defined as a 10-year risk ≥5 % for SCORE and as a 10-year risk ≥20 % for Framingham. r. recalibrated