Table 3.
Obstetrical Outcomes Among Women With and Women Without Epilepsy at Delivery Hospitalization
| Outcomea | Women, No. (%)b | OR (95% CI) | ||
|---|---|---|---|---|
| With Epilepsy (n = 69 385) |
Without Epilepsy (n = 20 449 532) |
Crude | Adjustedc | |
| Death | 56 (0.080) | 1294 (0.006) | 12.66 (9.68-16.56) |
11.46 (8.64-15.19) |
| Severe maternal morbidity | 588 (4.2) | 70 754 (1.7) | 2.53 (2.44-2.62) |
2.53 (2.44-2.63) |
| Cesarean delivery | 28 132 (40.5) | 6 763 068 (33.1) | 1.38 (1.36-1.40) |
1.40 (1.38-1.42) |
| Induction of labor | 14 339 (20.7) | 3 709 883 (18.1) | 1.18 (1.15-1.20) |
1.14 (1.12-1.16) |
| LOS, mean (SE), d | ||||
| Cesarean delivery | 4.0 (0.07) | 3.6 (0.02) | NA | NA |
| Vaginal delivery | 2.5 (0.03) | 2.2 (0.01) | NA | NA |
| Length of stay >6 d | ||||
| Cesarean delivery | 1865 (6.6) | 217 853 (3.2) | 2.14 (2.04-2.24) |
2.13 (2.03-2.23) |
| Vaginal delivery | 745 (1.8) | 88 360 (0.6) | 2.83 (2.63-3.05) |
2.60 (2.41-2.80) |
| Pregnancy-related hypertension |
7268 (10.5) | 1 611 070 (7.9) | 1.37 (1.34-1.40) |
1.30 (1.27-1.33) |
| Gestational hypertension | 2703 (3.9) | 779 016 (3.8) | 1.02 (0.99-1.06) |
0.96 (0.92-1.00) |
| Preeclampsia | 4629 (6.7) | 849 877 (4.2) | 1.65 (1.60-1.70) |
1.59 (1.54-1.63) |
| Seizures among preeclamptic patients |
394 (8.5) | 14 981 (1.8) | 5.18 (4.67-5.75) |
5.18 (4.65-5.77) |
| Antepartum hemorrhage | 1464 (2.1) | 312 428 (1.5) | 1.39 (1.32-1.47) |
1.38 (1.31-1.45) |
| Postpartum hemorrhage | ||||
| Due to atony | 1626 (2.3) | 438 978 (2.1) | 1.09 (1.04-1.15) |
1.14 (1.08-1.20) |
| Not due to atony | 621 (0.9) | 132 911 (0.6) | 1.38 (1.28-1.50) |
1.38 (1.28-1.50) |
| Severe postpartum hemorrhage |
490 (0.7) | 84 587 (0.4) | 1.71 (1.57-1.87) |
1.76 (1.61-1.93) |
| Gestational diabetes | 3981 (5.7) | 1 168 111 (5.7) | 1.01 (0.97-1.04) |
1.11 (1.07-1.15) |
| Preterm labor | 7716 (11.1) | 1 510 382 (7.4) | 1.57 (1.53-1.61) |
1.54 (1.50-1.57) |
| Premature rupture of membranes |
2791 (4.0) | 779 315 (3.8) | 1.06 (1.02-1.10) |
1.07 (1.03-1.11) |
| Chorioamnionitis | 1351 (1.9) | 361 402 (1.8) | 1.10 (1.05-1.17) |
1.17 (1.11-1.23) |
| Poor fetal growth | 2533 (3.7) | 432 779 (2.1) | 1.75 (1.68-1.82) |
1.68 (1.61-1.75) |
| Excessive fetal growth | 1330 (1.9) | 534 267 (2.6) | 0.73 (0.69-0.77) |
0.73 (0.69-0.77) |
| Fetal distress | 10 374 (15.0) | 2 924 175 (14.3) | 1.06 (1.03-1.08) |
1.04 (1.02-1.06) |
| Fetal abnormalities, any | 1605 (2.3) | 285 826 (1.4) | 1.67 (1.59-1.76) |
1.68 (1.60-1.77) |
| Stillbirth | 577 (0.8) | 125 543 (0.6) | 1.36 (1.25-1.48) |
1.27 (1.17-1.38) |
Abbreviations: LOS, length of stay; NA, not applicable; OR, odds ratio.
a
Outcomes are not mutually exclusive.
b
Because of a small degree of missing data, percentages may not exactly reflect the denominators provided. Data weighted using sampling weights to achieve nationally representative estimates.
c
Adjusted for maternal age, race, quartile of median household income for patient’s zip code, hospital location, hospital region, and year.