Skip to main content
. Author manuscript; available in PMC: 2017 Jan 1.
Published in final edited form as: Virology. 2015 Nov 6;487:230–241. doi: 10.1016/j.virol.2015.09.023

Fig. 1.

Fig. 1

Alphaviruses deficient in nuclear functions, but not their wt variants, induce high levels of IFN-β. (A) The schematic representation of alphavirus genomes encoding wt and mutated nsP2- and capsid-coding genes (SINV/G/GFP and VEEV/GFP/Cm, respectively). (B) NIH 3T3 cells were infected with the indicated viruses at an MOI of 20 PFU/cell. Media were harvested at 16 h post infection and used for assessment of both virus titers and IFN-β levels. Means of three biological repeats with SD are presented.