. Author manuscript; available in PMC: 2016 Jan 21.

Published in final edited form as: Cancer Prev Res (Phila). 2015 Apr 20;8(7):583–589. doi: 10.1158/1940-6207.CAPR-15-0101

Table 2.

Overall survival after oropharyngeal, base of tongue, and tonsil carcinoma by history of tonsillectomy^a

	Any age				<60 years				≥60 years
History of tonsillectomy	N_cases	Dead	HR^b (95% Cl)	HR^c (95% Cl)	N_cases	Dead	HR^b (95% Cl)	HR^c (95% Cl)	N_cases	Dead	HR^b (95% Cl)	HR^c (95% Cl)
Oropharyngeal carcinoma overall
No tonsillectomy or tonsillitis	4,825	3,064	1.00	1.00	2,593	1,601	1.00	1.00	2,232	1,463	1.00	1.00
Tonsillectomy <1 year before OPC	174	45	0.5 (0.4–0.6)	0.6 (0.4–0.7)	106	24	0.4 (0.3–0.6)	0.5 (0.3–0.8)	68	21	0.5 (0.4–0.7)	0.6 (0.4–0.8)
Tonsillectomy ≥1 year before OPC	52	25	1.0 (0.7–1.5)	1.3 (0.9–1.9)	29	13	1.4 (0.8–2.4)	1.9 (1.1–3.2)	23	12	0.7 (0.4–1.3)	1.0 (0.6–1.6)
Base of tongue carcinoma
No tonsillectomy or tonsillitis	727	413	1.00	1.00	386	213	1.00	1.00	341	200	1.00	1.00
Tonsillectomy <1 year before base of tongue carcinoma	16	7	0.8 (0.4–1.5)	1.0 (0.5–2.1)	10	4	0.8 (0.3–2.1)	1.2 (0.4–3.3)	6	3	0.9 (0.3–2.4)	1.0 (0.4–2.8)
Tonsillectomy ≥1 year before base of tongue carcinoma	10	5	0.7 (0.3–1.8)	1.0 (0.4–2.3)	4	1	0.5 (0.07–3.7)	0.7 (0.09–5.2)	6	4	0.7 (0.3–1.9)	1.1 (0.4–2.9)
Tonsil carcinoma
No tonsillectomy or tonsillitis	2,608	1,623	1.00	1.00	1,462	868	1.00	1.00	1,146	755	1.00	1.00
Tonsillectomy <1 year before tonsil carcinoma	123	26	0.4 (0.3–0.6)	0.5 (0.4–0.7)	75	15	0.4 (0.2–0.7)	0.5 (0.3–0.8)	48	11	0.5 (0.3–0.7)	0.5 (0.3–0.8)
Tonsillectomy ≥1 year before tonsil carcinoma	12	6	1.1 (0.5–2.3)	1.3 (0.6–2.6)	4	3	2.4 (0.8–7.3)	2.1 (0.7–6.5)	8	3	0.7 (0.3–1.8)	0.9 (0.3–2.4)

NOTE: Bolded estimates are significant.

Abbreviation: OPC, oropharyngeal carcinoma.

Estimates have been rounded to one significant digit for presentation in this table.

Crude.

Adjusted for attained age, calendar period, education and gender.