Table 1. The inhibition efficiency of Fasudil and FSD-C10 on ROCK activity.
Compound | Unit (nM) | ROCK I ATP con. (3.6 μM) | ROCK II ATP con. (5.3 μM) |
---|---|---|---|
Fasudil | IC50 | 385 | 344 |
FSD-C10 | IC50 | 1141 | 711 |
Positive control | IC50 | 1.7 | 0.93 |
Negative control | IC50 | >10000 | >10000 |