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. 2015 Sep 10;35(5):e00247. doi: 10.1042/BSR20150032

Table 1. The inhibition efficiency of Fasudil and FSD-C10 on ROCK activity.

Compound Unit (nM) ROCK I ATP con. (3.6 μM) ROCK II ATP con. (5.3 μM)
Fasudil IC50 385 344
FSD-C10 IC50 1141 711
Positive control IC50 1.7 0.93
Negative control IC50 >10000 >10000