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. Author manuscript; available in PMC: 2016 Jan 21.
Published in final edited form as: J Clin Cell Immunol. 2015 Oct 28;6(5):362. doi: 10.4172/2155-9899.1000362

Figure 4.

Figure 4

Overexpression of miR-24 inhibits early Aa-LPS induced IL-10 production in resting but not classically primed macrophages. IL-10 levels in the culture supernatant of macrophages transfected with miR-24 mimic, inhibitor, control mimic (all at 50 nM), or positive control (untransfected) for 18 h, primed with IFN-γ (10 ng/ml), IFN-γ plus TNF-α (1 ng/ml), IFN-γ+TNF-β (1 ng/ml), IFN-γ plus IL-17A (10 ng/ml), or positive control (no cytokine priming) for 18 h, and stimulated with Aa-LPS (100 ng/ml) for 96 h, was assayed by ELISA. A, B, C=Mean values, error bars (standard deviation), and significance calculated by ANOVA). n=4 biological donors. (*P<0.05, **P<0.001).