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. Author manuscript; available in PMC: 2016 Mar 1.
Published in final edited form as: Bioessays. 2015 Jul 22;37(9):936–941. doi: 10.1002/bies.201500060

Figure 1.

Figure 1

EBER2 facilitates binding of PAX5 to TRs via RNA-RNA interaction with nascent transcripts. A: The two accessible regions of EBER2 are marked in green, one of which engages in RNA-RNA interaction with nascent transcripts from the TR regions. PAX5 binding to EBER2 is indicated. B: A single TR unit of EBV and of RLV is shown; the EBER2-interacting region and PAX5 consensus sites are indicated (top). The predicted RNA-RNA interaction between EBER2 and the TR RNA is shown for EBV and RLV (bottom). C: Model for cellular ncRNAs in guiding interacting TFs to target sites by base pairing with nascent transcripts.