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. 2016 Jan 21;11(1):e0146622. doi: 10.1371/journal.pone.0146622

Fig 5. Polarization of CD3+ lymphocytes by whole tumour-lysate pulsed DCs.

Fig 5

To examine the nature of T-cell responses induced by whole tumour-lysate pulsed DCs, syngeneic naïve T-cells from MMTV-Ras mice were cultured with either unloaded DCs or TAA-DCs for 1-3-5-7- days and both T cell- and DC-derived cytokines were measured. ELISA quantified released type 1 [IFN-γ (A), IL-12 (C)] and type 2 [IL-10 (B)] cytokines in the supernatants. Results are expressed as mean values ± standard error of three independent experiments. *P value < 0.05; **P value <0.005.